Androgenic alopecia (AGA) is the androgen (male sex hormone)-dependent progressive loss of scalp hair that follows a defined pattern different in men and women. In general, the mechanism of hair loss is the binding of dihudroepiandrosterone (DHT, or weak androgen) to the androgen receptor (AR). DHT is converted to stronger androgens by the enzyme 5 alpha-reductase. In predisposed individuals’ scalps, there are high levels of DHT and AR and lower levels of 5 alpha-reductase.

So here is the perfect storm:                               

  1. High levels of weak androgen (DHT)
  2. High expression of androgen receptors on the surface of the cells in the hair follicles 
  3. Low activity of 5 alpha-reductase.

 

The final result: receptors of the hair-producing cells are saturated with weak androgens and cause hair loss. Current available nonsurgical treatment modalities with proven efficacy are oral finasteride, a competitive inhibitor of type two 5 alpha-reductase, and topical minoxidil, an adenosine-triphosphate-sensitive potassium channel opener which has been reported to stimulate the production of vascular endothelial growth factor.

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In the last 10 years, significant advances have been made in the understanding of the functions of the medicinal signaling cells and micro vesicles. Now there is more evidence that they can be used in the treatment of acute and chronic infections and autoimmune disorders.

  1. What is BIA-ALCL?

It is a form of Non-Hodgkin T-cell lymphoma which develops in women with breast implants.

  • Behaves differently from the systemic ALCL and resembles skin lymphoma.
  • Grows slowly and has favorable prognosis
  • It Is not breast cancer
  • It occurs more frequently in women with textured breast implants, but it has been found also in women with smooth breast implants.
  • Has been diagnosed in women with saline and silicone breast implants.

In the last 10 years, significant advances have been made in the understanding of the functions of the medicinal signaling cells and micro vesicles, as well as the role in fat grafting in cosmetic and reconstructive procedures. The population of this country, especially the aging population, is in demand for less invasive and more effective procedures. In the future, avant-garde groups of surgeons will continue to replace invasive procedures with tremendous down times with minimally invasive alternatives. A perfect example is autologous fat grafting. Although first battled by many, especially the “academic” surgeons and “reputable” societies, it is now the base for evolutionary and Nobel treatments. A lot of the medicinal signaling cell treatments are nothing but advanced fat transfer treatments. Some call them “ hype,” but some called the earth flat not that long ago.

Ultrasound versus Lasers in Body Contouring

An individual’s figure can negatively impact and fluctuate with the deteriorating age, fluctuating weight, and pre or post pregnancy and due to the lack of regular exercise. Today, everyone is busy and gets the least time to relax, the amount of stress is increasing day by day and so is the development of fatty tissue. Many people start bothering about their looks and appeal.

Diet and Exercise Resistant Fat Deposits, especially in certain areas, are also a significant health risk.

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